Table of Contents
- Deep Dive in IBDP Biology: D.2.2 Gene Expression (HL ONLY) Teacher Resource Pack
- 1. Start Strong Every Day: Bell Ringers and Exit Tickets
- 2. Bring Gene Expression to Life with Creative Projects
- 3. Solidify Understanding with Assessments and Practice
- 4. Complete Curriculum Alignment
- Why IBDP Educators Love This Bundle
- Inspire Insight and Innovation in Gene Expression
Deep Dive in IBDP Biology: D.2.2 Gene Expression (HL ONLY) Teacher Resource Pack
Activate Curiosity: Complete Resource Bundle for IBDP Biology D.2.2 Gene Expression
Understanding gene expression is key to unlocking the complexity of life itself. In IBDP Biology Topic D.2.2, students explore how genes are turned on and off, how cells specialize, and how environmental factors can impact genetic outcomes. These concepts form the basis of modern biology—from evolution and development to cancer research and biotechnology.
To help educators teach this high-level topic effectively, we’ve curated a comprehensive, classroom-ready resource bundle that aligns perfectly with the IBDP curriculum. Designed for engagement, clarity, and assessment success, these materials help students think deeply about gene regulation, epigenetics, and real-world applications.
1. Start Strong Every Day: Bell Ringers and Exit Tickets
Bell Ringers are short, focused prompts that activate prior knowledge and preview new content. They cover critical questions such as:
What is gene expression and why isn’t every gene expressed in every cell?
How do transcription factors and enhancers regulate transcription?
Why does mRNA stability vary between different cell types?
What is the difference between genome, transcriptome, and proteome?
Exit Tickets provide reflective closure at the end of lessons and foster metacognition. Topics include:
The importance of DNA methylation and histone modification
How epigenetic tags are inherited and reset during reproduction
The role of environmental triggers like pollution or diet in gene expression
Case-based questions about twins, inheritance, and environmental differences
These tools are ideal for daily formative assessment, driving home key concepts in short bursts.
2. Bring Gene Expression to Life with Creative Projects
Gene Expression Comic Strip
This imaginative project helps students visualize and internalize the central dogma. Students illustrate:
Transcription of DNA into mRNA
Translation of mRNA into protein
Protein folding and resulting phenotypic expression
By transforming a complex biochemical process into a visual story, students deepen their conceptual understanding while demonstrating creativity, narrative skills, and scientific accuracy.
Design a New Organism’s Gene Expression System
In this synthesis activity, students create a fictional organism adapted to a unique environment (e.g., desert, deep sea, or arctic tundra). They must:
Design a gene expression system customized to survival traits
Explain how environmental triggers regulate gene activation
Incorporate transcription, translation, and epigenetic mechanisms
The project emphasizes systems thinking and real-world relevance by connecting molecular biology with evolution, ecology, and biotechnology.
3. Solidify Understanding with Assessments and Practice
Multiple-Choice and Fill-in-the-Blank Quiz
This formative assessment includes:
Gene regulation mechanisms (transcription factors, promoter methylation)
Epigenetic tags like DNA methylation and histone modification
Differences between genome, transcriptome, and proteome
Environmental influences (e.g., air pollution altering methylation)
Epigenetic inheritance (e.g., effects in tigons, ligers, and twins)
Sample Questions:
What happens to most epigenetic tags during gamete formation? (Answer: Most are removed, some remain)
Which structure initiates transcription? (Answer: Promoter region)
What is the effect of cytosine methylation? (Answer: Decreased transcription)
Paper 1A Practice with Mark Scheme
This IB-style exam includes sets covering:
Overview of gene expression and protein synthesis
Regulation through transcription factors and epigenetic mechanisms
Environmental impacts such as pollution-induced methylation changes
Real-world applications including cancer, inheritance, and adaptive evolution
Complete with data-based questions and scenarios like methylation differences in smokers vs. non-smokers, it ensures students are fully prepared for IB-style assessments.
4. Complete Curriculum Alignment
The bundle fully supports all D.2.2 subtopics:
| Subtopic | Resources |
|---|---|
| D.2.2.1 – Definition of gene expression | Bell ringers, quiz, comic strip |
| D.2.2.2 – Transcription regulation | Bell ringers, quiz, Paper 1A |
| D.2.2.3 – mRNA stability | Exit tickets, Paper 1A |
| D.2.2.4 – Epigenesis and differentiation | Comic strip, bell ringers |
| D.2.2.5 – Genome, transcriptome, proteome | Bell ringers, quiz |
| D.2.2.6 – DNA methylation as an epigenetic tag | Quiz, bell ringers, Paper 1A |
| D.2.2.7 – Epigenetic inheritance | Exit tickets, quiz |
| D.2.2.8 – Environmental influences | Paper 1A, exit tickets |
| D.2.2.9 – Tag removal during reproduction | Quiz, bell ringers |
| D.2.2.10 – Twin studies | Bell ringers, quiz, Paper 1A |
Why IBDP Educators Love This Bundle
✔️ 100% aligned with the latest IBDP Biology syllabus
✔️ Includes creative projects that foster deeper learning
✔️ Builds critical thinking, creativity, and real-world application
✔️ Ready-to-use assessments and editable templates
✔️ Supports visual, auditory, and kinesthetic learners
Inspire Insight and Innovation in Gene Expression
The D.2.2 Gene Expression Resource Bundle empowers IB educators to move beyond memorization—engaging students in meaningful, cross-disciplinary biology. From understanding how genes are switched on and off, to exploring how air pollution might affect methylation patterns, this resource suite turns classrooms into laboratories of exploration and discovery.
Explore the full bundle today and bring gene expression to life for your students.
DP BIO D.2.2 Gene Expression (HL ONLY) Teacher Resource Pack
$49.00
Help students explore genetic control, cell processes, and osmoregulation with Edspry’s downloadable teaching pack—designed for Theme D: Continuity and Change – Cells. Aligned with the 2023 IB Diploma Biology subject guide, this all-in-one resource pack includes classroom-ready tools for standard… read more