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Deep Dive in IBDP Biology: D.2.2 Gene Expression (HL ONLY) Teacher Resource Pack


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Deep Dive in IBDP Biology: D.2.2 Gene Expression (HL ONLY) Teacher Resource Pack

Activate Curiosity: Complete Resource Bundle for IBDP Biology D.2.2 Gene Expression

Understanding gene expression is key to unlocking the complexity of life itself. In IBDP Biology Topic D.2.2, students explore how genes are turned on and off, how cells specialize, and how environmental factors can impact genetic outcomes. These concepts form the basis of modern biology—from evolution and development to cancer research and biotechnology.

To help educators teach this high-level topic effectively, we’ve curated a comprehensive, classroom-ready resource bundle that aligns perfectly with the IBDP curriculum. Designed for engagement, clarity, and assessment success, these materials help students think deeply about gene regulation, epigenetics, and real-world applications.


1. Start Strong Every Day: Bell Ringers and Exit Tickets

Bell Ringers are short, focused prompts that activate prior knowledge and preview new content. They cover critical questions such as:

  • What is gene expression and why isn’t every gene expressed in every cell?

  • How do transcription factors and enhancers regulate transcription?

  • Why does mRNA stability vary between different cell types?

  • What is the difference between genome, transcriptome, and proteome?

Exit Tickets provide reflective closure at the end of lessons and foster metacognition. Topics include:

  • The importance of DNA methylation and histone modification

  • How epigenetic tags are inherited and reset during reproduction

  • The role of environmental triggers like pollution or diet in gene expression

  • Case-based questions about twins, inheritance, and environmental differences

These tools are ideal for daily formative assessment, driving home key concepts in short bursts.


2. Bring Gene Expression to Life with Creative Projects

Gene Expression Comic Strip

This imaginative project helps students visualize and internalize the central dogma. Students illustrate:

  • Transcription of DNA into mRNA

  • Translation of mRNA into protein

  • Protein folding and resulting phenotypic expression

By transforming a complex biochemical process into a visual story, students deepen their conceptual understanding while demonstrating creativity, narrative skills, and scientific accuracy.

Design a New Organism’s Gene Expression System

In this synthesis activity, students create a fictional organism adapted to a unique environment (e.g., desert, deep sea, or arctic tundra). They must:

  • Design a gene expression system customized to survival traits

  • Explain how environmental triggers regulate gene activation

  • Incorporate transcription, translation, and epigenetic mechanisms

The project emphasizes systems thinking and real-world relevance by connecting molecular biology with evolution, ecology, and biotechnology.


3. Solidify Understanding with Assessments and Practice

Multiple-Choice and Fill-in-the-Blank Quiz

This formative assessment includes:

  • Gene regulation mechanisms (transcription factors, promoter methylation)

  • Epigenetic tags like DNA methylation and histone modification

  • Differences between genome, transcriptome, and proteome

  • Environmental influences (e.g., air pollution altering methylation)

  • Epigenetic inheritance (e.g., effects in tigons, ligers, and twins)

Sample Questions:

  • What happens to most epigenetic tags during gamete formation? (Answer: Most are removed, some remain)

  • Which structure initiates transcription? (Answer: Promoter region)

  • What is the effect of cytosine methylation? (Answer: Decreased transcription)

Paper 1A Practice with Mark Scheme

This IB-style exam includes sets covering:

  • Overview of gene expression and protein synthesis

  • Regulation through transcription factors and epigenetic mechanisms

  • Environmental impacts such as pollution-induced methylation changes

  • Real-world applications including cancer, inheritance, and adaptive evolution

Complete with data-based questions and scenarios like methylation differences in smokers vs. non-smokers, it ensures students are fully prepared for IB-style assessments.


4. Complete Curriculum Alignment

The bundle fully supports all D.2.2 subtopics:

SubtopicResources
D.2.2.1 – Definition of gene expressionBell ringers, quiz, comic strip
D.2.2.2 – Transcription regulationBell ringers, quiz, Paper 1A
D.2.2.3 – mRNA stabilityExit tickets, Paper 1A
D.2.2.4 – Epigenesis and differentiationComic strip, bell ringers
D.2.2.5 – Genome, transcriptome, proteomeBell ringers, quiz
D.2.2.6 – DNA methylation as an epigenetic tagQuiz, bell ringers, Paper 1A
D.2.2.7 – Epigenetic inheritanceExit tickets, quiz
D.2.2.8 – Environmental influencesPaper 1A, exit tickets
D.2.2.9 – Tag removal during reproductionQuiz, bell ringers
D.2.2.10 – Twin studiesBell ringers, quiz, Paper 1A

Why IBDP Educators Love This Bundle

✔️ 100% aligned with the latest IBDP Biology syllabus
✔️ Includes creative projects that foster deeper learning
✔️ Builds critical thinking, creativity, and real-world application
✔️ Ready-to-use assessments and editable templates
✔️ Supports visual, auditory, and kinesthetic learners


Inspire Insight and Innovation in Gene Expression

The D.2.2 Gene Expression Resource Bundle empowers IB educators to move beyond memorization—engaging students in meaningful, cross-disciplinary biology. From understanding how genes are switched on and off, to exploring how air pollution might affect methylation patterns, this resource suite turns classrooms into laboratories of exploration and discovery.

Explore the full bundle today and bring gene expression to life for your students.

DP BIO D.2.2 Gene Expression (HL ONLY) Teacher Resource Pack

DP BIO D.2.2 Gene Expression (HL ONLY) Teacher Resource Pack

$49.00

Help students explore genetic control, cell processes, and osmoregulation with Edspry’s downloadable teaching pack—designed for Theme D: Continuity and Change – Cells. Aligned with the 2023 IB Diploma Biology subject guide, this all-in-one resource pack includes classroom-ready tools for standard… read more


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